Decentralized Science
June 5, 2025

Infographic: Decentralized Science Vs. Traditional Science

By:
Tereza Bizkova & Drew Simon
Decentralized Science (DeSci) leverages Web3 mechanisms to address pain points in traditional science including centralized governance, precarious funding, a lack of access to data, and unfair compensation. Crypto mechanisms like decentralized funding models, IP-NFTs, tokenized research, and blockchain-based coordination tools offer a new approach to scientists seeking the next great discovery.

Traditional Science vs. Decentralized Science

How Web3 technology is reshaping scientific discovery

Traditional Science

Institutional Gatekeeping

Research is shaped by centralized institutions like universities, pharmaceutical companies, and grant agencies. These groups decide what gets funded, who participates, and what counts as legitimate work.

Unreliable Funding Paths

Scientists often spend large amounts of time applying for grants, with funding favoring established fields or familiar methods. This can make it hard for newer or riskier ideas to get support.

Limited Data Access

Access to research papers and datasets is often restricted or paywalled. This slows down collaboration, makes it harder to verify results, and limits who can build on existing work.

Profit-Driven Incentives

Research tends to follow what is profitable or likely to be published, directing funding toward patents and prestige. Topics with less commercial appeal, such as open-access medicine or climate solutions, are often overlooked.

Centralized Credit and Pay

Recognition and revenue often flow through institutions and publishers. Scientists, reviewers, and contributors may be underpaid or excluded from decision-making and long-term value.

Decentralized Science (DeSci)

Community-Guided Research

Decentralized autonomous organizations (DAOs) and other collaborative models give researchers and communities a bigger say in setting research priorities. This creates space for overlooked topics and locally relevant work.

Modular, Peer-Driven Funding

New approaches like quadratic funding, tokenized research, and microgrants offer more flexible ways to support early-stage or interdisciplinary work, especially in areas that traditional funders tend to ignore.

Open Protocols for Collaboration

DeSci projects often share data, methods, and progress updates in open formats or on decentralized networks. This improves transparency, makes replication easier, and helps teams build on each other's work more effectively.

Public-Good Science First

DeSci makes it easier to fund research that serves broad public needs, such as rare diseases, preventative health, or climate resilience, even when there’s no obvious commercial return.

Contributor-Owned Rewards

Tokens, open attribution, and retroactive funding help recognize everyone involved in the research process—not just senior authors or institutions, but also peer reviewers, developers, and organizers.

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